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Flor / Diener / Meyer group

Principal investigator:
Institut für Neuropsychologie und Klinische Psychologie
Zentralinstitut für Seelische Gesundheit (ZI)
J5, D-68159 Mannheim


General research interests and goals:

Focal point of the psychobiological research at the department of Cognitive and Clinical Neuroscience is the exploration of the interaction between brain and behavior, i.e. how behavior and experience affect neuronal processes and how, in turn, neuronal changes affect behavior and experience. This question is studied both in healthy humans as well as in persons with mental, psychophysiological, and somatic disorders, where learning and memory processes and their neural substrates are thought to be affected. In addition, we also take a life-span perspective on neural alterations related to learning and memory by investigating healthy older age individuals and persons prone to develop dementia. A further objective of research at the department is the development of adequate assessment procedures and novel behavioral therapy approaches. We employ neuropsychological, clinical and experimental psychological methods, psychophysiological and neuroimaging measures as well as genetic approaches. For the treatment of mental disorders, several behavioral intervention strategies, some combined with pharmacological treatments (e.g., d-cycloserine, hydrocortisone, cannabis, and dextromethorphan), are tested. Finally, the department focuses on virtual and augmented reality applications and brain computer interfaces for the treatment of maladaptive brain plasticity.



Current group members:

PhD students: Michael Hoppstaedter / Christian Baeuchl

Key publications:

Jia T, Macare C, Desrivieres S, Gonzalez D A, Tao C, Ji X, Flor H, Consortium I (2016) Neural basis of reward anticipation and its genetic determinants Proceedings of the National Academy of Sciences of the United States of America 113(14), 3879-3884 .
Kuner R, Flor H (2016) Structural plasticity and reorganisation in chronic pain Nature reviews. Neuroscience, 18(1), 20-30 .
Baeuchl C, Meyer P, Hoppstadter M, Diener C, Flor H (2015) Contextual fear conditioning in humans using feature-identical contexts. Neurobiol Learn Mem, 121:1-11 .
Hoppstädter M, Baeuchl C, Diener C, Flor H, Meyer, P (2015) Simultaneous EEG and fMRI reveals the brain networks underlying recognition memory ERP old/new effects Neuroimage,116:112-122 .
Whelan R, Conrod P J, Poline J B, Lourdusamy A, Banaschewski T, Barker G J, Flor H Consortium, I (2012) Adolescent impulsivity phenotypes characterized by distinct brain networks Nat Neurosci, 15(6), 920-925 .